Supplements: How much is too much?

-Apr 22, Sara Palmer Hussey, PhD, Nutrition -

We all know that the modern diet doesn’t always contain enough nutrients to help us look and feel our best, despite our best intentions. Whilst supplementing is becoming a more popular practice by women of all ages, we have noticed a worrying trend of people taking vast piles of supplements in the belief that any supplement must be good for them. But is that really the case?


We decided to investigate and find out.


Supplements often contain more than 100% of recommended daily intakes of vitamins and minerals. If this is added to what we are already integrating from our diets, we may exceed tolerable upper intake levels. Is there a real risk of toxicity from supplements?

Excess amounts of any vitamins and minerals can lead to imbalances in the body that influence the absorption and function of other essential nutrients, as well as counterbalancing themselves. 

Vitamins are divided into fat-soluble and water-soluble. Fat-soluble vitamins, such as vitamins A, D, E and K, can be stored in the body, in fatty tissue and liver tissue, and released as needed. Water-soluble vitamins, such as the B vitamins and vitamin C, are not stored in the body and, therefore, a daily supply is needed.

As the body usually excretes excess water-soluble vitamins, we have often concluded that we need not worry about toxicity with these vitamins. However, recent studies have linked excess vitamin C to kidney stones and excess vitamin B6 to nerve problems. Although the levels at which toxicity can become a problem for these two nutrients lie over 2000% and 4000% of the recommended daily intake respectively, it is no longer unusual to see the levels of some nutrients in supplements reach levels close to those figures.

Folic acid is essential for preventing birth defects, but excess amounts interfere with the absorption of vitamin B12. With a tolerable upper level of just 1mg (250% of the recommended daily intake) and many foods now fortified with this nutrient, it is not impossible to exceed this value regularly.

Toxicity is a greater concern regarding fat-soluble vitamins, which can accumulate in fatty tissue over time and lead to a condition known as hypervitaminosis. Excess vitamin A during pregnancy can lead to birth defects, excess levels of vitamin E can increase the probability of haemorrhages and excess vitamin K can interfere with normal blood clotting.

Toxicity is also a concern regarding minerals. Excess calcium can impair kidney function and interfere with the absorption of iron and zinc. Excess selenium can lead to hair loss and nerve damage. Excess iron can interfere with zinc and copper absorption. Excess iodine can impair thyroid function.


Supplements - can you take too many?
If you take several different supplements, look at the labels of what you’re taking each day and add each one up to see if you’re taking unnecessarily vast amounts of nutrients, if you have high amounts of one or several nutrients, you could be damaging your health rather than helping it.


If our diet is healthy and balanced, it is best not to take a supplement with any nutrient included at levels over 100% of the recommended daily allowance. It is also advisable to check the nutrient content of our diets and note whether any of the foods we habitually consume are fortified with certain vitamins and minerals (for example, in cereals, bread, soft drinks, health bars, multivitamins, etc.), which, together with any supplements we may be taking, could take our total intake over tolerable upper limits. It is obviously ill-advised to exceed the dosage recommendations specified on the packaging of any supplement.


Which nutrients are we likely to be deficient in?


So, in what nutrients are we likely to be deficient in our modern diet? The World Health Organization considers that more than 2 billion people worldwide suffer from vitamin and mineral deficiencies, primarily iodine, iron, vitamin A and zinc, with iron, zinc and iodine deficiencies being those most prevalent in the developed world.

According to the World Health Organisation, iron deficiency is the number one micronutrient deficiency in both developing and developed countries. “The major health consequences include poor pregnancy outcome, impaired physical and cognitive development, increased risk of morbidity in children and reduced work productivity in adults. Anaemia contributes to 20% of all maternal deaths.” In our diets, making sure we eat vitamin C (e.g. oranges and cruciferous veg) together with any plant source of iron (e.g. dark, leafy vegetables, lentils, chickpeas) will greatly enhance iron absorption, while the best sources are liver, meat, oysters and sardines.

It is estimated that over 2 billion people in the world today suffer from iodine deficiency, including about 50% of all Europeans. Iodine deficiency can result in thyroid problems, such as goiter, and mental disorders, such as cretinism. Having been almost completely depleted from our soils, the best sources of iodine now include seafood and iodised salt.

A lack of zinc can manifest in numerous ways as it affects so many organ systems, including the skin, gastrointestinal tract, the central nervous system, the immune system, the skeletal system and the reproductive system. Stores of zinc in the body are drastically depleted by stress and illness and requirements are increased by exercise and growth (e.g. during childhood and pregnancy). The best sources of zinc in our diet include oysters, meat, beans and nuts.

If we are able to identify specific nutritional deficiencies in our bodies and readdress them through diet, we will certainly feel improvements. However, are there any supplements that we can use to bring about positive results to our health and appearance that could not be achieved through diet alone?


The lowdown on amino acids


Therapeutic levels of certain amino acids have been found to give tangible health improvements. Those most widely researched include L-carnitine, L-cysteine, L-lysine, L-arginine, L-glutamine and L-alanine.

Carnitine is essential to energy production. It transports fatty acids into the mitochondria so that they can be used as fuel to produce energy. It also transports toxic compounds generated during normal cell function out of the cell to prevent their accumulation. A sufficient supply of carnitine prevents mental and physical fatigue and is commonly used, therefore, to improve mental and physical endurance.

Although the body produces carnitine from the amino acids lysine and methionine in the liver and kidneys, as well as assimilating it from sources such as red meat (the redder the meat, the higher the carnitine content), studies have found that integrating this nutrient in a supplement offers health benefits over and above those provided by diet alone. It has been shown to slow the decline in mitochondrial function that is a characteristic of ageing and it is beneficial in cardiovascular disease, type II diabetes, cancer, HIV and AIDS and male infertility.


What is Gluathione?


The body uses L-cysteine to make glutathione, its own powerful antioxidant. Antioxidants neutralise free radicals, which are harmful by-products of cellular activity that damage cell membranes and DNA. Free radicals have been identified as primary factors in the onset of ageing and the development of a number of illnesses, including heart disease and cancer.

The most effective detoxifier in the body, glutathione also recycles other antioxidants to sustain our on-going attack on free radicals. Pollution, medication, stress, ageing, illness, infections and radiation all deplete our levels of glutathione. Supplementing our diets with L-Cysteine and L-glutamine (another building block for glutathione) to sustain glutathione at youthful concentrations will optimise our overall level of health.


How HGH helps our skin stay youthful


As we age, falling levels of Human Growth Hormone correspond to a loss of vitality and result in extra body fat, reduced muscle tissue, slow healing, lack of elasticity in the skin and reduced immune function. HGH is responsible for cell regeneration and repair throughout the body. Hormone-replacement therapies using GH (Growth Hormone), DHEA (dehydroepiandrosterone) or pregnenolone do nothing to actually improve the body’s own natural hormonal release.

However, the amino-acid combination L-arginine, L-lysine and L-glutamine rather than introducing foreign hormones into our bodies to increase levels in circulation, actually promotes a natural improvement in our own HGH release from the pituitary gland itself, thus stimulating rather than curtailing its optimum functioning. It works by removing an impediment to HGH release, somatostatin, that increases with age and by providing the building blocks for HGH synthesis.


As well as boosting levels of HGH, these three amino acids boost levels of collagen and elastin in the skin, increase lean muscle mass, muscle strength and endurance and support the immune system.


All of us want to feel healthy. But how much is too much and can taking piles of multi-vitamins actually make you sick?


Certain safe herbal extracts that we may not integrate into our diets on a daily basis could also provide significant health benefits when taken as a daily supplement. These include turmeric, which helps address chronic inflammation, garlic, which has been shown to reduce the incidence of certain cancers, and milk thistle, which can be useful in addressing liver disorders.

The growing use of supplements in general reflects a wholesome interest in nutrition and the role it plays in preserving good health. It also reveals the desire to take a greater, more active responsibility for our own health. This trend is mirrored in sectors relating to other factors that influence good health, such as exercise and stress management. If supplementation is used wisely to safely guard against possible deficiencies in our diet as well as to maintain healthy levels of important nutrients in a targeted approach, it can certainly be an important tool in our quest for optimum health throughout our lives.

And, that’s certainly why supplementing sensibly, with a quality, clean all natural one that has been formulated by an expert to give you everything you need but nothing extra that you don’t, is such an useful tool for great health and wellbeing. There’s no need to take lots of other vitamins as well, your body doesn’t need them.


Love this? Find out here if your vitamin pills are made with toxic ingredients. Are you at risk of a vitamin D deficiency? – here’s how to spot the signs. Are supermarket vitamins a waste of money? – find out here. And, if you’re in the mood for some probiotics, here’s how to make your own.

Lumity has been carefully formulated to contain all the nutrients you need to support a healthy, balanced diet and nothing that it doesn’t require. Please remember that this article is not a substitute for medical advice and if you’re worried about your nutrient intake or are considering taking supplements you should always talk to your doctor.

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