What are cellular energy decline and cellular debris and how do they affect ageing?

-Jul 15, Sara Palmer Hussey, PhD, Health -

If you’re interested in how the body ages and ways to slow that process, two factors – cellular energy decline and cellular debris – stand out. So, what are cellular energy decline and cellular debris and how do they affect ageing?

One of the cell components at risk of free radical damage is the mitochondria, the cell’s energy-producing organelles. If the mitochondria of the cells are affected by free radical attack or a shortage of fuel, the cell’s ability to produce sufficient energy for all its tasks will be diminished. Once the cell’s energy turnover has been compromised, the cell no longer operates in optimum efficiency, but instead has to prioritise the importance of its tasks. Elimination of waste products gets relegated to the bottom of its list of things to do and so debris begins to accumulate, which in turn begins to further hamper the clean efficiency of the cell’s processes. The cell will wait for sufficient energy to take the rubbish out, but if energy levels continue to dwindle, this situation becomes a vicious circle with the build-up of debris further hampering the efficiency of the cell.

Are there any nutrients we can supplement with that help the body deal with cellular energy decline and cellular debris?

One nutrient that greatly aids the transport of fuel into the cell and the efficient production of energy within the mitochondria of the cell is acetyl-l-carnitine. As energy levels increase, the cell is able to reverse the degenerative process created by the accumulation of debris and move back towards efficiency. Acetyl-l-carnitine’s ability to boost the elimination of debris and restore energy turnover in all cells offers tangible improvements to fatigue.

What’s the most important nutrient for people over 30 to take?

Coenzyme Q10 is also an essential component of healthy mitochondrial function. Ageing humans have been found to have over 50% less Coenzyme Q10 on average compared to that of young adults. This finding makes Coenzyme Q10 one of the most important nutrients for people over 30 to integrate.

Can magnesium help slow the ageing process?

The energy produced by the mitochondria must be bound to a magnesium ion in order to be biologically active. Sufficient magnesium is, therefore, essential for youthful energy levels. Magnesium is essential also to the permeability of the mitochondrial membrane and to the transfer and, therefore, utilisation of energy. 

Is insulin resistance the reason behind chronic tiredness?

Insulin resistance is also a factor responsible for blocking the entry of fuel into the cell and impeding the generation of energy. Insulin is the hormone secreted by the pancreas that lowers blood sugar by promoting its transport from the blood stream into cells. 

The modern diet, often too high in glucose, is responsible for an over-activation of insulin, which makes cells progressively resistant as a form of self-protection against persistent bombardment.

If glucose is not allowed into the cells then it remains in the blood stream, which prompts the production of more insulin in a vicious cycle that exacerbates the problem. Insulin resistant cells cannot take in glucose, amino acids or fatty acids. This inhibits energy production by stifling the fuel supply to the cell. Such fuel-starved cells will age much faster.

Are there other ways to have more energy as we age?

Nutrients such as acetyl-l-carnitine, coenzyme Q10 and omega-3 fatty acids, such as those in flaxseed oil, help increase insulin receptiveness by increasing the fluidity of the cell membrane. 

Lumity offers tangible improvements in mental and physical fatigue

Acetyl-l-Carnitine is found most abundantly in red meat. Exercise also naturally increases our levels of acetyl-l-carnitine. However, with increasingly sedentary lifestyles and lower consumption of red meat, our levels of carnitine are often far below those required for optimal health. Supplementation, therefore, can make a big difference. 

Acetyl-l-carnitine produces great results in the brain where cells divide very slowly and the accumulation of cellular debris is a bigger problem. In this way, Lumity offers tangible improvements in mental and physical fatigue. 

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